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How does Doxycycline work?
Doxycycline is given orally or IV in adults in a dosage of 200 mg in 2 divided doses on the first day, and thereafter 100 mg/day in a single daily dose or 2 divided doses; 100 mg q 12 h for the entire course of therapy has also been used. In children > 8 yr, 4 mg/kg/day divided in 2 doses is given orally or IV on the first day, and thereafter 2 mg/kg/day as a single daily dose or divided in 2 doses; 4 mg/kg/day divided in 2 doses has also been used for the whole course of therapy. Doses should be taken an hour before meals or 2 h after.
Doxycycline is the only tetracycline that does not require dosage adjustment in renal failure.
Doxycycline, also known as Doryx, Doxy or Vibramycin, is an effective treatment prescribed for individuals who have been exposed to all forms of Anthrax.
Who should NOT take Doxycycline without a doctor’s consent?
Those who have not been exposed to, or are not at risk to exposure of any form of Anthrax. Those who have liver disease should first consult a doctor. Anyone who has an unusual or allergic reaction to Doxycyline. Those who experience long exposure to sunlight should first consult a doctor. Pregnant women and women who are breastfeeding should first consult a doctor. -
Children under the age of 8 should not take Doxycyline since it can cause permanent yellow staining of the teeth.
What are the common side effects of Doxycyline?
If you experience any of the following serious side effects, stop taking Doxycycline and consult your health care provider immediately. Dark yellow or brown urine; difficulty breathing; increased sensitivity to the sun or ultraviolet light; headaches; itching in the rectal or genital area; stomach pain or cramps; skin rash or itching; tingling or numbness of the hands or feet; unusual bleeding or bruising; unusual tireness or weakness; yellowing or eyes or skin.
If you experience any of the following less serious side effects, talk to your doctor:
diarrhea; discolored tongue; loss of appetite; nausea, vomiting or sore mouth.
Contraindicators (drugs that should only be taken with a doctor’s permission while taking Doxycycline)
Do not take antacids that contain magnesium or aluminum (such as Tums or Rolaids); barbituate medicines for inducing sleep or treating seizures (convulsions); calcium salts; carbamazepine; cholestyramine; colestipol; digoxin; female hormones including contraceptive or birth control pills; ferrous sulfate; magnesium salts; other antibiotics; phenytoin; or sodium bicarbonate
Before taking Doxycycline, tell your doctor if you are taking any prescriptive medicines or over the counter medicines such as nutritional supplements, or herbal products. Also tell your doctor if you frequently drink caffeine or alcohol, if you smoke or if you use illegal drugs.
Dosages
The recommended adult dose of Doxycycline for exposure to all forms of Anthrax is 100 milligrams given orally every 12 hours. The recommended pediatric dose of Doxycycline (children 8 years of age and older) and less than 100 pounds is 1 mg per pound given orally every 12 hours.
Official Doxycycline Website
FDA Doxycycline Information
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Doxycycline
